How many employees work at Sema4 OpCo?

Sema4 OpCo, Inc. has approximately 148 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Sema4 OpCo’s total headcount has declined 30.7% from 214 employees in 2023 to 148 in 2026.

Data source: Revelio LabsCoverage: Global workforce, 20232026Published August 2026

Is Sema4 OpCo hiring right now?

Yes, Sema4 OpCo is actively hiring. Sema4 OpCo had 5 active job postings in 2026, a 85.7% increase from 2025 see job openings & hiring trends.

About Sema4 OpCo’s Workforce

Sema4 OpCo, Inc. is a Healthcare and Wellness Services company that employs 148 people worldwide as of March 2026. It is the 10th-largest by headcount among its peers. Founded in 2015, the company is headquartered in Stamford, Connecticut.

Sema4 OpCo's workforce has declined 30.7% from 2023 to 2026, down 5.4% year over year in 2026. It fell to a low of 148 in 2026 Q1 before recovering. Its workforce is concentrated most in North America (87.6%), followed by Sub-Saharan Africa (6.5%) and South Asia (2.8%).

Sema4 OpCo's functional groups are Finance and Operations (44.3%), Engineering (37.8%), and Sales and Marketing (17.9%). The average salary is $121,388, ranging from a median of $120,000 in North America to $5,000 in South Asia, down 3.4% year over year in 2026.

Sema4 OpCo's active job postings rose 85.7% in 2026 to 5. Overall employee sentiment is neutral but improving.

Sourced from Revelio Labs workforce data.

Headquarters
Stamford, Connecticut
Founded
2015
Industry
Healthcare and Wellness Services
Employees
148
YoY
-5.4% (-12)

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Sema4 OpCo Annual Employee Count (2023-2026)

Interactive chart of Sema4 OpCo annual worldwide employee count from 2023 to 2026.
  • Sema4 OpCo had 148 employees in 2026, a 5.4% decline (-12) from 2025.
  • Sema4 OpCo had 149 employees in 2025, a 6.1% decline (-14) from 2024.
  • Sema4 OpCo had 163 employees in 2024, a 7.6% decline (-16) from 2023.
  • Sema4 OpCo had 179 employees in 2023, a 44.9% decline (-287) from 2022.

Sema4 OpCo's total workforce has declined from 214 employees in 2023 to 148 in 2026.

Sema4 OpCo, Inc. quarterly employee count

YearQtrEmployeesYoY ChangeYoY %
2026Q1148-12-5.4%
2025Q4149-14-6.1%
2025Q3153-11-5.2%
2025Q2155-12-6.0%
2025Q1160-10-5.6%
2024Q4163-16-7.6%
2024Q3164-34-11.1%
2024Q2167-47-13.8%
2024Q1170-82-18.2%
2023Q4179-287-44.9%
2023Q3198-613-39.4%
2023Q2214-717-38.7%

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Sema4 OpCo Employee Count by Region (2026)

North America accounts for the largest share of Sema4 OpCo's global workforce with approximately 88% of total employees, followed by Sub-Saharan Africa and South Asia.

Sema4 OpCo employees by region

RegionEmployees% of Total
North America12987.6%
Sub-Saharan Africa96.5%
South Asia42.8%
South America21.4%
Central America and the Caribbean10.7%
Central and Western Asia10.5%
Southeast Asia10.5%

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Sema4 OpCo Employee Count by Department (2026)

Sema4 OpCo's employee groups are Finance and Operations (44.3%), Engineering (37.8%), and Sales and Marketing (17.9%).

Sema4 OpCo employees by department

DepartmentEmployees% of Total
Finance and Operations6544.3%
Engineering5637.8%
Sales and Marketing2617.9%

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Sema4 OpCo Employee Salary by Region (2026)

Sema4 OpCo's average employee salary is $121,388 globally. Employees in North America receive the highest compensation. Pay is lowest in South Asia, at a median of $5,000.

Sema4 OpCo median employee salary by region (USD)

RegionMedian Salary
North America$120,000
South America$7,000
South Asia$5,000

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Sema4 OpCo Job Openings and Hiring Trends (2023-2026)

Interactive chart of Sema4 OpCo annual active job postings from 2023 to 2026.
  • Sema4 OpCo had 5 active job postings in 2026, a 85.7% increase (+4) from 2025.
  • Sema4 OpCo had 1 active job postings in 2025, a 0% no change from 2024.
  • Sema4 OpCo had 1 active job postings in 2024, a 175.0% decline (-14) from 2023.
  • Sema4 OpCo had 15 active job postings in 2023, a 200.0% increase from 2022.
  • Hiring velocity in 2026: 2 new roles/month, up from 0 in 2025 and 3 in 2024.

Sema4 OpCo's active job postings rose 85.7% in 2026 to 5.

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Sema4 OpCo Employee Sentiment (2026)

Revelio Labs tracks employee sentiment across Sema4 OpCo's workforce based on public professional data. Overall sentiment is neutral and has improved year over year in 2026.

Overall

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Frequently Asked Questions About Sema4 OpCo

How fast is Sema4 OpCo growing?
In 2026, Sema4 OpCo's headcount shrank 5.4% to 148 employees, down from 160 in 2025.
See the full headcount history
Where are Sema4 OpCo employees located?
Most Sema4 OpCo employees are based in North America (87.6% of headcount), followed by Sub-Saharan Africa and South Asia.
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What is the average salary at Sema4 OpCo?
The average employee salary at Sema4 OpCo is approximately $121.4k per year.
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How many new job postings does Sema4 OpCo open per year?
In Q1 2026, Sema4 OpCo opened 5 new job postings. In 2025, Sema4 OpCo opened 4 new job postings — about 0 per month.
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When was Sema4 OpCo founded and where is it headquartered?
Sema4 OpCo was founded in 2015 and is headquartered in Stamford, Connecticut.
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